This resource provides coupling information of select GPCRs obtained using the Shedding Assay technique

Option 1: Search your GPCR



Option 2: Click from the list of GPCRs below

5-Hydroxytryptamine receptors

HTR1A
HTR1B
HTR1D
HTR1E
HTR1F
HTR2A
HTR2B
HTR2C
HTR4
HTR6
HTR7

Acetylcholine receptors (muscarinic)

CHRM1
CHRM2
CHRM3
CHRM4
CHRM5

Adenosine receptors

ADORA1
ADORA2A
ADORA2B
ADORA3

Adrenoceptors

ADRA1A
ADRA1B
ADRA1D
ADRA2A
ADRA2B
ADRA2C
ADRB1
ADRB2
ADRB3

Angiotensin receptors

AGTR1

Apelin receptor

APLNR

Bombesin receptors

GRPR
NMBR

Bradykinin receptors

BDKRB1
BDKRB2

Cannabinoid receptors

CNR1
CNR2

Cholecystokinin receptors

CCKAR
CCKBR

Class A Orphans

GPR119
GPR132
GPR17
GPR174
GPR183
GPR34
GPR35
GPR55
GPR84
MRGPRX1
MRGPRX2
P2RY10

Dopamine receptors

DRD1
DRD2
DRD3
DRD4
DRD5

Endothelin receptors

EDNRA
EDNRB

Formylpeptide receptors

FPR1
FPR2

Free fatty acid receptors

FFAR1
FFAR2
FFAR3
FFAR4

GPR18, GPR55 and GPR119

GPR119
GPR55

Galanin receptors

GALR1
GALR2
GALR3

Ghrelin receptor

GHSR

Glucagon receptor family

GIPR

Gonadotrophin-releasing hormone receptors

GNRHR

Histamine receptors

HRH1
HRH2
HRH3
HRH4

Kisspeptin receptor

KISS1R

Leukotriene receptors

CYSLTR1
CYSLTR2
FPR2
LTB4R
LTB4R2

Lysophospholipid (LPA) receptors

LPAR1
LPAR2
LPAR3
LPAR4
LPAR5
LPAR6

Lysophospholipid (S1P) receptors

S1PR1
S1PR2
S1PR3
S1PR5

Melanin-concentrating hormone receptors

MCHR1
MCHR2

Melanocortin receptors

MC1R
MC3R
MC4R
MC5R

Melatonin receptors

MTNR1A
MTNR1B

Motilin receptor

MLNR

Neuromedin U receptors

NMUR1
NMUR2

Neuropeptide FF/neuropeptide AF receptors

NPFFR1
NPFFR2

Neuropeptide W/neuropeptide B receptors

NPBWR1

Neurotensin receptors

NTSR1

Opioid receptors

OPRD1
OPRK1
OPRL1
OPRM1

Orexin receptors

HCRTR1
HCRTR2

Oxoglutarate receptor

OXGR1

P2Y receptors

P2RY1
P2RY11
P2RY12
P2RY13
P2RY14
P2RY2
P2RY4
P2RY6

Parathyroid hormone receptors

PTH1R
PTH2R

Platelet-activating factor receptor

PTAFR

Prolactin-releasing peptide receptor

PRLHR

Prostanoid receptors

PTGDR
PTGER1
PTGER2
PTGER3
PTGER4
PTGFR
PTGIR
TBXA2R

Proteinase-activated receptors

F2R
F2RL1
F2RL2
F2RL3

Somatostatin receptors

SSTR1
SSTR2
SSTR3
SSTR4
SSTR5

Tachykinin receptors

TACR1
TACR2
TACR3

Thyrotropin-releasing hormone receptors

TRHR

Urotensin receptor

UTS2R

VIP and PACAP receptors

ADCYAP1R1

Vasopressin and oxytocin receptors

AVPR1A
AVPR1B
AVPR2
OXTR

This resource is developed by the Russell lab at the University of Heidelberg, Germany in collaboration with Dr. Asuka Inoue's group at Tohoku University, Japan (2018)